Abstracts to publications by Rosetta Inpharmatics employees are available below. In some cases, supporting data is also available. Note: Current Rosetta Inpharmatics employees are shown in boldface type.
Comprehensive evaluation of isoprenoid biosynthesis regulation in Saccharomyces cerevisiae utilizing the Genome Reporter Matrix.
J. Lipid Research 40:850-860 (1999).
D. Dimster-Denk, J. Rine, J. Phillips, S. Scherer, Paige Cundiff, Kristin DeBord, Doug Gilliland, Scott Hickman, Amy Jarvis, Lisa Tong, and Matthew Ashby.
How DNA microarrays and expression profiling will affect clinical practice.
British Medical Journal 319:1-2 (1999).
Stephen H. Friend, Rosetta Inpharmatics, Kirkland, WA
Synthetic DNA Arrays.
Genetic Engineering (N Y) 20:111-123 (1998).
Alan Blanchard, Rosetta Inpharmatics, Kirkland, WA
Cheap DNA arrays-it's not all smoke and mirrors.
Nature Biotechnology 17:953 (1999).
Alan Blanchard and Stephen Friend, Rosetta Inpharmatics, Kirkland, WA
Genetic Selection of Peptide Inhibitors of Biological Pathways.
Science 285:591-595 (1999).
T. C. Norman, D. L. Smith, P. K. Sorger, B. L. Drees, S. M. O'Rourke, Timothy R. Hughes, Christopher J. Roberts, Stephen H. Friend, S. Fields, and A. W. Murray.
Gene Expression Informatics--It's All in Your Mine.
Nature Genetics 21 (supplement):51-55 (1999).
Douglas E. Bassett Jr., M. B. Eisen, and M. S. Boguski.
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.
Science 285:901-906 (1999).
E. A. Winzeler, Daniel D. Shoemaker, A. Astromoff, H. Liang, Sally Whelen Dow, Stephen H. Friend, Christopher J. Roberts, Terry Ward, R. W. Davis et al.
Genomic profiling of drug sensitivities via induced haploinsufficiency.
Nature Genetics 21:278-283 (1999).
G. Giaever, Daniel D. Shoemaker, T. W. Jones, H. Liang, E. A. Winzeler, A. Astromoff, and R. Davis.
Drug Target Validation and Identification of Secondary Drug Target Effects Using DNA Microarrays.
Nature Medicine 4:1293-1301 (1998).
Matthew J. Marton, J. L. DeRisi, Holly A. Bennett, V. R. Iyer, Michael R. Meyer, Christopher J. Roberts, Roland Stoughton, Julja Burchard, David Slade, Hongyue Dai, Douglas E. Bassett Jr., Leland H. Hartwell, P. O. Brown, and Stephen H. Friend
Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy.
Nature Genetics 14:450-456 (1996).
Daniel D. Shoemaker, D. A. Lashkari, D. Morris, M. Mittmann, and R. W. Davis.
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