Abstracts to publications by Rosetta Inpharmatics employees are avaiable below.In some cases, supporting data is also available. Note: Current Rosetta Inpharmatics employees are shown in boldface type.
Regulation of gene expression by lithium and depletion of inositol in slices of adult rat cortex.
Neuron. 2005 Mar 24;45(6):861-72.
Philip E. Brandish1, Ming Su1, Daniel J. Holder1, Paul Hodor1, John Szumiloski1, Robert R. Kleinhanz2, Jaime E. Forbes2, Mollie E. McWhorter2, Sven J. Duenwald2, Mark L. Parrish2, Sang Na1, Yuan Liu1, Robert L. Phillips1, John J. Renger1, Sethu Sankaranarayanan1, Adam J. Simon1 and Edward M. Scolnick3
1Merck & Co., Inc., West Point, Pennsylvania 19486
2Rosetta Inpharmatics LLC, a wholly owned subsidiary of Merck & Co. Inc., 401 Terry Avenue North, Seattle, Washington 98011
3 Present address: The Broad Institute, One Kendall Square, Cambridge, Massachusetts 02139
Cis-acting expression quantitative trait loci in mice.
Genome Res. 2005 May;15(5):681-91. Epub 2005 Apr 18.
Sudheer Doss1, Eric E. Schadt6, Thomas A. Drake3 and Aldons J. Lusis1,2,4,5,7
1 Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA;
2 Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA;
3 Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA;
4 Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA;
5 Molecular Biology Institute, UCLA, Los Angeles, California 90095, USA;
6 Rosetta Inpharmatics, A wholly owned subsidiary of Merck & Co., Inc., Kirkland, Washington 98034, USA
Ultrafine Mapping of SNPs From Mouse Strains C57BL/6J, DBA/2J, and C57BLKS/J for Loci Contributing to Diabetes and Atherosclerosis Susceptibility.
Diabetes. 2005 Apr;54(4):1191-9.
Richard C. Davis1, Eric E. Schadt2, Alessandra C.L. Cervino2, Miklós Péterfy1,3, and Aldons J. Lusis1,4
1 Departments of Medicine and Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, California
2 Rosetta Inpharmatics, Merck and Company, Seattle, Washington
3 Veterans Administration, Greater Los Angeles Healthcare System, Los Angeles, California
4 Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California
Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments.
Trends Genet. 2005 Feb;21(2):93-102
Jason M. Johnsona, Stephen Edwardsa, Daniel Shoemakerb and Eric E. Schadta
aRosetta Inpharmatics LLC*, 401 Terry Avenue North, Seattle, WA 98109, USA
bGHC Technologies, 505 Coast Boulevard South, Suite 309, La Jolla, CA 92037, USA
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.
Nature. 2005 Feb 17;433(7027):769-73
Lee P. Lim1, Nelson C. Lau2, Philip Garrett-Engele1, Andrew Grimson2, Janell M. Schelter1, John Castle1, David P. Bartel2, Peter S. Linsley1 and Jason M. Johnson1
1Rosetta Inpharmatics (wholly owned subsidiary of Merck and Co.), 401 Terry Avenue N, Seattle, Washington 98109, USA
2Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology,
New look at an old costimulator.
Nat Immunol. 2005 Mar;6(3):231-2.
Linsley PS.
Synthetic shRNAs as potent RNAi triggers.
Nat Biotechnol. 2005 Feb;23(2):227-31
Despina Siolas1, 2, Cara Lerner3, Julja Burchard3, Wei Ge3, Peter S Linsley3, Patrick J Paddison2, Gregory J Hannon2 & Michele A Cleary3
1 Program in Genetics, Stony Brook University, Stony Brook, New York 11794, USA.
2 Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
3 Rosetta Inpharmatics, LLC, a wholly owned subsidiary of Merck and Co., Inc., 401 Terry North, Seattle, Washington 98109, USA.
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