Abstracts to publications by Rosetta Inpharmatics employees are available below. In some cases, supporting data is also available. Note: Current Rosetta Inpharmatics employees are shown in boldface type.

Role of Scaffolds in MAP Kinase Pathway Specificity Revealed by Custom Design of Pathway-dedicated Signaling Proteins
Current Biology 2001, 11:1815–1824

Kendra Harris, Rachel E. Lamson, Bryce Nelson, Timothy R. Hughes, Matthew J. Marton, Christopher J. Roberts, Charles Boone and Peter M. Pryciak

Clustering of Hepatotoxins Based on Mechanism of Toxicity Using Gene Expression Profiles
Toxicology and Applied Pharmacology 175, 28–42 (2001)

Jeffrey F. Waring, Robert A. Jolly, Rita Ciurlionis, Pek Yee Lum, Jens T. Praestgaard, David C. Morfitt, Bruno Buratto, Chris Roberts, Eric Schadt, and Roger G. Ulrich

Transcriptional Profiling Shows that Gcn4p is a Master Regulator of Gene Expression During Amino Acid Starvation in Yeast
Molecular and Cellular Biology 21, 4347-4368 (2001).

Krishnamurthy Natarajan, Michael R. Meyer, Belinda M. Jackson, David Slade, Christopher Roberts, Alan G. Hinnebusch and Matthew J. Marton

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer
Nature Biotech 19: 342-347 (2001).

Timothy R. Hughes, Mao Mao, Allan R. Jones, Julja Burchard, Matthew J. Marton, Karen W. Shannon, Steven M. Lefkowitz, Michael Ziman, Janell M. Schelter, Michael R. Meyer, Sumire Kobayashi, Colleen Davis, Hongyue Dai, Yudong D. He, Sergey B. Stephaniants, Guy Cavet, Wynn L. Walker, Anne West, Ernest Coffey, Daniel D. Shoemaker, Roland Stoughton, Alan P. Blanchard, Stephen H. Friend, and Peter S. Linsley

Experimental Annotation of the Human Genome Using Microarray Technology
Nature 409: 922-927 (2001).

D.D. Shoemaker*, E.E. Schadt*, C.D. Armour, Y.D. He, P. Garrett-Engele, P.D. McDonagh, P.M. Loerch, A. Leonardson, P.Y. Lum, G. Cavet, L.F. Wu, S.J. Altschuler, S. Edwards, J. King, J.S. Tsang, G. Schimmack, J.M. Schelter, J. Koch, M. Ziman, M.J. Marton, B. Li, P. Cundiff, T. Ward, J. Castle, M. Krolewski, M.R. Meyer, M. Mao, J. Burchard, M.J. Kidd, H. Dai, J.W. Phillips, P.S. Linsley, R. Stoughton, S. Scherer & M.S. Boguski
*These authors contributed equally to this work.

Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data.
J Cell Biochem Suppl. 2001;Suppl 37:120-5.

Schadt EE¹, Li C, Ellis B, Wong WH.

¹Department of Biomathematics
University of California
Los Angeles, California, USA.
eschadt@rosetta.org

Microarrays - the 21st century divining rod?
Nature Medicine. 7, 658-659 (2001).

Yudong D. He and Stephen H. Friend